There’s New Proof Crispr Can Edit Genes Inside Human Bodies

The Crispr components can’t naturally get into cells on their own, so Intellia uses a delivery system called lipid nanoparticles—essentially tiny fat bubbles—to ferry them to the liver. In Intellia’s trials, patients receive a one-time IV infusion of these Crispr-laden nanoparticles into the veins in their arms. Since blood passes through the liver, lipid nanoparticles can easily travel there from the bloodstream. In the liver, the nanoparticles are taken up by cells called hepatocytes. Once inside these cells, the nanoparticles break down and let Crispr get to work editing out the problematic gene.

In both diseases, a genetic mutation allows an aberrant protein to run amok and cause damage. In

→ Continue reading at Wired - Science

More from author

Related posts

Advertisment

Latest posts

49ers Hufanga is ‘everybody’s favorite’; Kittle debut nears; Armstead still out

San Francisco 49ers’ Talanoa Hufanga reacts after intercepting a pass during the first half of an NFL football game against...

Photos: Senior Safari draws hundreds to Happy Hollow Park & Zoo

SAN JOSE, CALIFORNIA – September 22: Senior Safari program participant Ginny Barret, 70, of San Jose reacts as she pets...

Analysis: Enjoy your Airbnb — just don't forget to do the laundry and take out the trash

But renters are getting increasingly fed up with lists of do's and don'ts that await them inside. Strip the beds, wash the linens, load...