The U.S. now has a drug for severe frostbite. How does it work?

In the worst cases, frostbite can cause the tissues in fingers, toes, noses and other extremities to die and require amputation. Now doctors in the United States have a way to save patients from these life-altering effects.

In February, the U.S. Food and Drug Administration approved the country’s first medication to treat severe frostbite. In a clinical trial, the drug, iloprost, greatly reduced amputations in nearly all the frostbite patients who received it.

Although frostbite affects a relatively small number of people in the United States — a few thousand annually — it is a major concern for people who must spend a lot of time outside in the

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