The $6 Billion Shot at Making New Antibiotics

Dustin Brown, a slight, dark-haired guy who lives in southwest Indiana, is 36, married, and a stay-at-home dad. He never expected to achieve any of those milestones: wife, toddler son, moving away from his family in Kentucky. Not even adulthood. Brown has cystic fibrosis, an inherited disorder that clogs major organs with sticky, sludgy mucus and makes them breeding grounds for infections. When he was born, newly diagnosed patients weren’t expected to survive past elementary school.

That the roughly 40,000 CF patients in the US have managed to beat that prediction is due to better treatments—just three years ago, the US Food

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