The Case of the Incredibly Long-Lived Mouse Cells

“It’s probably one of the most extraordinary papers in immunology that I’ve seen, easily in the past decade,” says John Wherry, director of the Institute of Immunology at the University of Pennsylvania’s Perelman School of Medicine, who was not involved in the study. “It tells us that immunity can be incredibly durable, if we understand how to generate it properly.” 

Andrew Soerens, a postdoctoral immunologist who inherited the project 21 immunizations in, didn’t expect it to become his main responsibility. “It felt like it could be the worst project ever, because it had no endpoint in mind. Or, it could be pretty cool because it was interesting biology,” he recalls. 

This project is

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