Not Everyone Loses Weight on Ozempic

Danielle Rosas had tried all the usual avenues to lose weight—modifying her diet, increasing her exercise—but the weight always came back. In 2020, she turned to Ozempic. She was 225 pounds at the time. “My weight has fluctuated a lot throughout my adulthood,” says Rosas, now 36.

After three months of injecting the drug once a week, she’d lost about 5 percent of her body weight, around 15 pounds. She was disappointed. She had hoped to lose more—in trials, patients had lost three times as much, although over a much longer period. What’s worse, she felt nauseous and generally unwell a lot of the time. She thought the side effects

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