Flu Is Relentless. Crispr Might Be Able to Shut It Down

As he addressed an audience of virologists from China, Australia, and Singapore at October’s Pandemic Research Alliance Symposium, Wei Zhao introduced an eye-catching idea.

The gene-editing technology Crispr is best known for delivering groundbreaking new therapies for rare diseases, tweaking or knocking out rogue genes in conditions ranging from sickle cell disease to hemophilia. But Zhao and his colleagues at Melbourne’s Peter Doherty Institute for Infection and Immunity have envisioned a new application.

They believe Crispr could be tailored to create a next-generation treatment for influenza, whether that’s the seasonal strains which plague both the northern and southern hemispheres on an annual basis or the worrisome new variants in birds and

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