Certain immune cells backstab their cellular coworkers during allergic reactions.
Mast cells, the security patrols of the immune system, can trigger allergic inflammation when they run into unfamiliar proteins (SN: 9/5/07). For the first time, researchers have seen these overeager cells attract and trap other key immune cells, then expel their hostages’ inflammatory chemicals in a process dubbed nexocytosis. The discovery may help scientists understand the root causes of health conditions involving allergies or the immune system, such as asthma and dermatitis.
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