The US Food and Drug Administration says it is investigating cases in which some patients who received a type of cutting-edge cancer treatment later developed new cancers.
Known as CAR-T cell therapy, the treatment involves removing certain immune cells called T cells from patients and genetically modifying them to find and attack cancer. Since 2017, the FDA has approved six commercial CAR-T cell therapies, all for blood cancers such as leukemias and lymphomas. Researchers are also testing these promising therapies for a range of other cancers, as well as autoimmune diseases.
Now, the agency is probing reports of some patients’ T cells becoming cancerous after receiving these therapies. The FDA said
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