How Cells Resist the Pressure of the Deep Sea

The original version of this story appeared in Quanta Magazine.

The bottom of the ocean is cold, dark, and under extreme pressure. It is not a place suited to the physiology of us surface dwellers: At the deepest point, the pressure of 36,200 feet of seawater is greater than the weight of an elephant on every square inch of your body. Yet Earth’s deepest places are home to life uniquely suited to these challenging conditions. Scientists have studied how the bodies of some large animals, such as anglerfish and blobfish, have adapted to withstand the pressure. But far less is known about how cells and molecules stand up to the

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