Add to that: There’s little past experience with the vaccine, known as Jynneos in the US, being used against this disease. It was only approved by the US Food and Drug Administration in 2019, primarily for the prevention of smallpox in case that virus—eradicated from circulation by an earlier vaccine, but retained in two labs—was ever used as a biological weapon. Jynneos underwent human safety studies but was never tested for efficacy against monkeypox in people; those estimates are based on animal work. It has never been available commercially in the US, but
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