The tiny blobs of lab-grown human brain tissue were just specks, each measuring a few millimeters in diameter. Researchers at Stanford University made them by cultivating human stem cells into three-dimensional clumps of tissue. Called brain organoids, these simplified structures contain some of the cells and properties of a real human brain, offering insight into development and neurological conditions.
But they’re not nearly as complex as the real thing, so to boost their realism, researchers elsewhere have tried transplanting human organoids into the brains of rodents. In past experiments, those cells failed to integrate into the animals’ brains. This time, it worked: The organoids formed connections with the animals’ own
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