Adult mouse brains are teeming with ‘silent synapses’

Learning lots of new information as a baby requires a pool of ready-to-go, immature connections between nerve cells to form memories quickly. Called silent synapses, these connections are inactive until summoned to help create memories, and were thought to be present mainly in the developing brain and die off with time. But a new study reveals that there are many silent synapses in the adult mouse brain, researchers report November 30 in Nature.

Neuroscientists have long puzzled over how the adult human brain can have stable, long-term memories, while at the same time maintaining a certain flexibility to be able to make new memories, a concept known as plasticity

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